abstract：OBJECTIVE:Among postmenopausal women, those with diabetes experience more cardiovascular diseases than those without diabetes. We examine the relationship of hormone replacement therapy (HRT) with indicators of lipid and glucose metabolism using a national sample of diabetic and nondiabetic postmenopausal women. RESEA...

journal_title：Diabetes care

authors： Crespo CJ,Smit E,Snelling A,Sempos CT,Andersen RE,NHANES III.

更新日期：2002-10-01 00:00:00

abstract：OBJECTIVE:Therapies with metformin, sulfonylureas, or insulin improve glycemic control in the short term but do not prevent progressive islet beta-cell failure or long-term deterioration in glycemia. Our goal was to evaluate, in patients recently diagnosed with type 2 diabetes (<3 years), the long-term efficacy of mono...

journal_title：Diabetes care

authors： Viberti G,Kahn SE,Greene DA,Herman WH,Zinman B,Holman RR,Haffner SM,Levy D,Lachin JM,Berry RA,Heise MA,Jones NP,Freed MI

更新日期：2002-10-01 00:00:00

abstract：:OBJECTIVE-Impaired endothelial function of resistance and conduit arteries can be detected in patients with type 1 diabetes. We studied whether a persistent improvement of endothelial function can be achieved by regular physical training. RESEARCH DESIGN AND METHODS-The study included 26 patients with type 1 diabetes ...

journal_title：Diabetes care

authors： Fuchsjäger-Mayrl G,Pleiner J,Wiesinger GF,Sieder AE,Quittan M,Nuhr MJ,Francesconi C,Seit HP,Francesconi M,Schmetterer L,Wolzt M

更新日期：2002-10-01 00:00:00

abstract：OBJECTIVE:Our objective was to compare the performance of oral glucose tolerance tests (OGTTs) and multivariate models incorporating commonly available clinical variables in their ability to predict future cardiovascular disease (CVD). RESEARCH DESIGN AND METHODS:We randomly selected 2,662 Mexican-Americans and 1,595 ...

journal_title：Diabetes care

authors： Stern MP,Fatehi P,Williams K,Haffner SM

更新日期：2002-10-01 00:00:00

abstract：OBJECTIVE:Conjugated linoleic acid (CLA) is a group of dietary fatty acids with antiobesity and antidiabetic effects in some animals. The trans10cis12 (t10c12) CLA isomer seems to cause these effects, including improved insulin sensitivity. Whether such isomer-specific effects occur in humans is unknown. The aim of thi...

journal_title：Diabetes care

authors： Risérus U,Arner P,Brismar K,Vessby B

更新日期：2002-09-01 00:00:00

abstract：OBJECTIVE:To determine whether a culturally appropriate clinic- and community-based intervention for African-American women with type 2 diabetes will increase moderate-intensity physical activity (PA). RESEARCH DESIGN AND METHODS:In this randomized controlled trial conducted at seven practices in central North Carolin...

journal_title：Diabetes care

authors： Keyserling TC,Samuel-Hodge CD,Ammerman AS,Ainsworth BE,Henríquez-Roldán CF,Elasy TA,Skelly AH,Johnston LF,Bangdiwala SI

更新日期：2002-09-01 00:00:00

abstract：OBJECTIVE:Exercise tolerance in patients with diabetes is frequently impaired due to noncardiac disease such as claudication and polyneuropathy. This study assesses the prognostic value of dobutamine stress myocardial perfusion imaging in patients with diabetes. RESEARCH DESIGN AND METHODS:A total of 207 consecutive d...

journal_title：Diabetes care

authors： Schinkel AF,Elhendy A,van Domburg RT,Bax JJ,Vourvouri EC,Sozzi FB,Valkema R,Roelandt JR,Poldermans D

更新日期：2002-09-01 00:00:00

abstract：OBJECTIVE:To compare the effects of repaglinide, glipizide, and glibenclamide on insulin secretion and postprandial glucose after a single standard 500-kcal test meal. RESEARCH DESIGN AND METHODS:A total of 12 type 2 diabetic patients with early diabetes (mean HbA(1c) of 6.1%) and 12 matched control subjects were enro...

journal_title：Diabetes care

authors： Cozma LS,Luzio SD,Dunseath GJ,Langendorg KW,Pieber T,Owens DR

更新日期：2002-08-01 00:00:00

abstract：OBJECTIVE:Inflammatory markers predict type 2 diabetes and relate to the metabolic syndrome. Gestational diabetes mellitus (GDM) predicts type 2 diabetes and may be part of this syndrome. To examine the association of inflammatory markers with GDM, we investigated total sialic acid (TSA) in women with and without previ...

journal_title：Diabetes care

authors： Sriharan M,Reichelt AJ,Opperman ML,Duncan BB,Mengue SS,Crook MA,Schmidt MI

更新日期：2002-08-01 00:00:00

abstract：OBJECTIVE:To investigate the prevalence of beta-cell autoantigen-reactive peripheral T-cells in type 1 diabetes, we developed an immunoglobulin-free enzyme-linked immunospot (ELISPOT) assay and assessed its usefulness for diagnosing this disease. RESEARCH DESIGN AND METHODS:Cellular immune responses to beta -cell auto...

journal_title：Diabetes care

authors： Kotani R,Nagata M,Moriyama H,Nakayama M,Yamada K,Chowdhury SA,Chakrabarty S,Jin Z,Yasuda H,Yokono K

更新日期：2002-08-01 00:00:00

abstract：OBJECTIVE:Differences in risk of erectile dysfunction (ED) by characteristics of diabetes among older men are not well understood. We examined the association of type and duration of diabetes with erectile function in men >50 years of age in a large prospective cohort study. RESEARCH DESIGN AND METHODS:Subjects includ...

journal_title：Diabetes care

authors： Bacon CG,Hu FB,Giovannucci E,Glasser DB,Mittleman MA,Rimm EB

更新日期：2002-08-01 00:00:00

abstract：OBJECTIVE:To evaluate whether homeostasis model assessment-estimated insulin resistance (HOMA-IR) is an independent predictor of cardiovascular disease (CVD) in type 2 diabetes. RESEARCH DESIGN AND METHODS:Conventional CVD risk factors (sex, age, smoking, plasma lipids, blood pressure, and metabolic control) and insul...

journal_title：Diabetes care

authors： Bonora E,Formentini G,Calcaterra F,Lombardi S,Marini F,Zenari L,Saggiani F,Poli M,Perbellini S,Raffaelli A,Cacciatori V,Santi L,Targher G,Bonadonna R,Muggeo M

更新日期：2002-07-01 00:00:00

abstract：OBJECTIVE:To test the utility of homeostasis model assessment (HOMA) in predicting insulin sensitivity [x10(- 4) min(-1)/(microIU/ml)] in children and to develop and compare two new prediction equations for insulin sensitivity in children using demographic and anthropometric measures in the presence or absence of fasti...

journal_title：Diabetes care

authors： Huang TT,Johnson MS,Goran MI

更新日期：2002-07-01 00:00:00

abstract：OBJECTIVE:Despite being a safe, effective therapy for lowering cardiovascular risk, only 20% of diabetic patients were using aspirin in the early 1990s. This study examines current physician practices and the use of aspirin therapy by individuals with diabetes. RESEARCH DESIGN AND METHODS:A random sample of diabetic p...

journal_title：Diabetes care

authors： Krein SL,Vijan S,Pogach LM,Hogan MM,Kerr EA

更新日期：2002-06-01 00:00:00

abstract：OBJECTIVE:We studied the associations between 1) current use of oral contraceptives (OCs) and 2) glucose levels, insulin levels, and diabetes in young women. RESEARCH DESIGN AND METHODS:Subjects were women (n = 1,940) in the Coronary Artery Risk Development in Young Adults (CARDIA) study, a prospective observational s...

journal_title：Diabetes care

authors： Kim C,Siscovick DS,Sidney S,Lewis CE,Kiefe CI,Koepsell TD,CARDIA Study.

更新日期：2002-06-01 00:00:00

abstract：OBJECTIVE:To identify hormonal, psychological, and demographic predictors of symptom detection and accuracy of blood glucose estimation during mild hypoglycemia in adolescents and young adults with type 1 diabetes. RESEARCH DESIGN AND METHODS:During an insulin-glucose clamp study, 53 adolescents and 19 young adults es...

journal_title：Diabetes care

authors： Ryan CM,Dulay D,Suprasongsin C,Becker DJ

更新日期：2002-05-01 00:00:00

abstract：OBJECTIVE:Delayed gastric emptying and/or gastrointestinal symptoms occur in 30-50% of diabetic patients. Known contributing factors are autonomic neuropathy and acute hyperglycemia, but the role of gastric autoimmunity has never been investigated, although 15-20% of type 1 diabetic patients exhibit parietal cell antib...

journal_title：Diabetes care

authors： De Block CE,De Leeuw IH,Pelckmans PA,Callens D,Máday E,Van Gaal LF

更新日期：2002-05-01 00:00:00

abstract：OBJECTIVE:To determine the effect of a high-protein (HP) diet compared with a low-protein (LP) diet on weight loss, resting energy expenditure (REE), and the thermic effect of food (TEF) in subjects with type 2 diabetes during moderate energy restriction. RESEARCH DESIGN AND METHODS:In this study, 26 obese subjects wi...

journal_title：Diabetes care

authors： Luscombe ND,Clifton PM,Noakes M,Parker B,Wittert G

更新日期：2002-04-01 00:00:00

abstract：OBJECTIVE:This study was performed to evaluate whether an additional dose of NPH insulin at lunchtime might overcome the deleterious effects of waning basal insulinemia on pre-dinner and evening glucose values during insulin lispro intensive therapy with once daily basal insulin at night. RESEARCH DESIGN AND METHODS:T...

journal_title：Diabetes care

authors： Stades AM,Hoekstra JB,van den Tweel I,Erkelens DW,Holleman F,STABILITY Study Group.

更新日期：2002-04-01 00:00:00

abstract：OBJECTIVE:To estimate the health-related quality of life (HRQOL) and treatment satisfaction for patients with type 2 diabetes in the Netherlands and to examine which patient characteristics are associated with quality of life and treatment satisfaction. RESEARCH DESIGN AND METHODS:For a sample of 1,348 type 2 diabetes...

journal_title：Diabetes care

authors： Redekop WK,Koopmanschap MA,Stolk RP,Rutten GE,Wolffenbuttel BH,Niessen LW

更新日期：2002-03-01 00:00:00

abstract：OBJECTIVE:To investigate the dose-response effects of pioglitazone on glycemic control, insulin sensitivity, and insulin secretion in patients with type 2 diabetes. RESEARCH DESIGN AND METHODS:A total of 58 diet-treated patients with type 2 diabetes (aged 54 +/- 1 years; 34 men and 24 women; BMI 31.5 +/- 0.6 kg/m(2)) ...

journal_title：Diabetes care

authors： Miyazaki Y,Matsuda M,DeFronzo RA

更新日期：2002-03-01 00:00:00

abstract：OBJECTIVES:To study the effect of water diuresis on renal medullary and cortical oxygenation in patients with diabetes using blood oxygenation level--dependent magnetic resonance imaging (BOLD MRI). RESEARCH DESIGN AND METHODS:Nine mild diabetic subjects (48 +/- 2.7 years of age, six women) and nine nondiabetic subjec...

journal_title：Diabetes care

authors： Epstein FH,Veves A,Prasad PV

更新日期：2002-03-01 00:00:00

abstract：OBJECTIVES:Obesity is a common condition in type 2 diabetic patients. Treating obesity may enhance hypoglycemic treatment and contribute to the reduction of long-term microvascular and macrovascular complications. Orlistat reduces cardiovascular risk factors in obese type 2 diabetic patients. The objectives of this stu...

journal_title：Diabetes care

authors： Lamotte M,Annemans L,Lefever A,Nechelput M,Masure J

更新日期：2002-02-01 00:00:00

abstract：OBJECTIVE:To prospectively examine the effect of weight loss 1 year after laparoscopic adjustable gastric band surgery on a broad range of health outcomes in 50 diabetic subjects. RESEARCH DESIGN AND METHODS:A total of 50 (17 men, 33 women) of 51 patients with type 2 diabetes, from a total of 500 consecutive patients,...

journal_title：Diabetes care

authors： Dixon JB,O'Brien PE

更新日期：2002-02-01 00:00:00

abstract：OBJECTIVE:To estimate incidence rates of diabetes and associated risk factors among participants of the Strong Heart Study. RESEARCH DESIGN AND METHODS:Of the 4,549 Strong Heart Study participants examined at baseline, 3,638 returned for a similar examination after an average of 4 years. The 1985 World Health Organiza...

journal_title：Diabetes care

authors： Lee ET,Welty TK,Cowan LD,Wang W,Rhoades DA,Devereux R,Go O,Fabsitz R,Howard BV

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVE:The sulfonylurea (SU) glyburide may cause severe and prolonged episodes of hypoglycemia. We aimed at investigating the impact of glyburide on glucose counterregulatory hormones during stepwise hypoglycemic clamp studies. RESEARCH DESIGN AND METHODS:We performed stepwise hypoglycemic clamp studies in 16 healt...

journal_title：Diabetes care

authors： ter Braak EW,Appelman AM,van der Tweel I,Erkelens DW,van Haeften TW

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVE:To assess the relationship between cigarette smoking and mortality among women with type 2 diabetes in the Nurses' Health Study cohort. RESEARCH DESIGN AND METHODS:The Nurses' Health Study, a prospective cohort of U.S. female registered nurses, included 7,401 women with type 2 diabetes diagnosed at baseline ...

journal_title：Diabetes care

authors： Al-Delaimy WK,Willett WC,Manson JE,Speizer FE,Hu FB

更新日期：2001-12-01 00:00:00

abstract：OBJECTIVE:In patients with type 2 diabetes, microalbuminuria is associated with an increase in predominantly cardiovascular mortality. Considerable interindividual variability in the rate of progression of microalbuminuria exists. The prognostic significance of rate of progression of microalbuminuria with regard to car...

journal_title：Diabetes care

authors： Spoelstra-de Man AM,Brouwer CB,Stehouwer CD,Smulders YM

更新日期：2001-12-01 00:00:00

abstract：OBJECTIVE:To determine the risk of frequent and severe hypoglycemia and the associated demographic and clinical risk factors. RESEARCH DESIGN AND METHODS:Demographic and diabetes self-management factors were measured in 415 subjects followed prospectively for 4-6.5 years of type 1 diabetes duration as participants in ...

journal_title：Diabetes care

authors： Allen C,LeCaire T,Palta M,Daniels K,Meredith M,D'Alessio DJ,Wisconsin Diabetes Registry Project.

更新日期：2001-11-01 00:00:00

abstract：OBJECTIVE:To project the number of people with diagnosed diabetes in the U.S. through 2050, accounting for changing demography and diabetes prevalence rates. RESEARCH DESIGN AND METHODS:We combined age-, sex-, and race-specific diagnosed diabetes prevalence rates-predicted from 1980-1998 trends in prevalence data from...

journal_title：Diabetes care

authors： Boyle JP,Honeycutt AA,Narayan KM,Hoerger TJ,Geiss LS,Chen H,Thompson TJ

更新日期：2001-11-01 00:00:00

abstract：OBJECTIVE:Insulin and glucose levels in response to premeal insulin lispro or repaglinide were evaluated in adult patients with cystic fibrosis-related diabetes (CFRD) without fasting hyperglycemia. RESEARCH DESIGN AND METHODS:Seven patients with CFRD were fed 1,000-kcal liquid mixed meals. Three study conditions were...

journal_title：Diabetes care

authors： Moran A,Phillips J,Milla C

更新日期：2001-10-01 00:00:00

abstract：OBJECTIVE:To examine the association of stage of change with diet and exercise behaviors in response to a lifestyle intervention for Native Hawaiians (NHs). RESEARCH DESIGN AND METHODS:A family ('ohana) support lifestyle intervention was compared with a standard intervention in NHs with or at risk for diabetes in two ...

journal_title：Diabetes care

authors： Mau MK,Glanz K,Severino R,Grove JS,Johnson B,Curb JD

更新日期：2001-10-01 00:00:00

abstract：OBJECTIVE:To determine whether elderly individuals with type 2 diabetes or impaired glucose tolerance are at increased risk for cognitive impairment compared with individuals with normal glucose tolerance. RESEARCH DESIGN AND METHODS:Elderly Hispanic individuals (n = 414) and non-Hispanic white individuals (n = 469) a...

journal_title：Diabetes care

authors： Lindeman RD,Romero LJ,LaRue A,Yau CL,Schade DS,Koehler KM,Baumgartner RN,Garry PJ,New Mexico Elder Health Survey.

更新日期：2001-09-01 00:00:00

abstract：OBJECTIVE:To study the influence of position changes on 24-h ambulatory blood pressure (ABP) in normotensive or mildly hypertensive normoalbuminuric patients with type 1 diabetes. RESEARCH DESIGN AND METHODS:A cross-sectional evaluation of patients was staged according to the duration of diabetes (DD) and the presence...

journal_title：Diabetes care

authors： Benhamou PY,Mouret S,Quesada JL,Boizel R,Baguet JP,Halimi S,Mallion JM

更新日期：2001-09-01 00:00:00

abstract：OBJECTIVE:To characterize the insulin sensitivity of overweight and obese 5- to 10-year-old (Tanner stage 1-3) African-American children screened for participation in a diabetes prevention study and to identify the association of insulin sensitivity with obesity, hyperlipidemia, and hypertension. RESEARCH DESIGN AND M...

journal_title：Diabetes care

authors： Young-Hyman D,Schlundt DG,Herman L,De Luca F,Counts D

更新日期：2001-08-01 00:00:00

abstract：OBJECTIVE:To determine the effect of diabetes on long-term survival after acute myocardial infarction and to compare its effect with that of a previous myocardial infarction. RESEARCH DESIGN AND METHODS:In a prospective cohort study, we followed 1,935 patients hospitalized with a confirmed acute myocardial infarction ...

journal_title：Diabetes care

authors： Mukamal KJ,Nesto RW,Cohen MC,Muller JE,Maclure M,Sherwood JB,Mittleman MA

更新日期：2001-08-01 00:00:00

abstract：OBJECTIVE:In patients with clinical hemochromatosis, the frequency of diabetes ranges from 20 to 50%, and the heterozygosity for the C282Y mutation in the HFE gene might be associated with an increased risk for diabetes. There are also some reports that suggest that iron overload might cause diabetic nephropathy. RESE...

journal_title：Diabetes care

authors： Moczulski DK,Grzeszczak W,Gawlik B

更新日期：2001-07-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis that intra-abdominal fat plays a primary role over general adiposity for metabolic abnormalities and atherosclerosis. RESEARCH DESIGN AND METHODS:We cross-sectionally studied 849 Japanese men aged 50.3 +/- 8.5 years (range 20-78) with BMI 23.5 +/- 2.9 kg/m(2). Intimal-medial thickness ...

journal_title：Diabetes care

authors： Takami R,Takeda N,Hayashi M,Sasaki A,Kawachi S,Yoshino K,Takami K,Nakashima K,Akai A,Yamakita N,Yasuda K

更新日期：2001-07-01 00:00:00

abstract：OBJECTIVE:To implement an educational program in 10 Latin American countries and to evaluate its effect on the clinical, biochemical, and therapeutic aspects as well as the economic cost of diabetes. RESEARCH DESIGN AND METHODS:Educators from each participating country were previously trained to implement the educatio...

journal_title：Diabetes care

authors： Gagliardino JJ,Etchegoyen G,PENDID-LA Research Group.

更新日期：2001-06-01 00:00:00

abstract：OBJECTIVE:Subjects with type 1 diabetes are at high risk for many long-term complications, including early mortality and coronary artery disease (CAD). Few data are available on which to base goal levels for two major risk factors, namely blood pressure and lipid/lipoproteins. The objective of this study was to determi...

journal_title：Diabetes care

authors： Orchard TJ,Forrest KY,Kuller LH,Becker DJ,Pittsburgh Epidemiology of Diabetes Complications Study.

更新日期：2001-06-01 00:00:00